有无视网膜病变的糖尿病患者焦虑、抑郁状态及影响因素分析

doi:10.3969/j.issn.0253-2778.2020.03.017

中国科学技术大学学报 ›› 2020, Vol. 50 ›› Issue (3): 382-388.DOI: 10.3969/j.issn.0253-2778.2020.03.017

• 论著 • 上一篇

有无视网膜病变的糖尿病患者焦虑、抑郁状态及影响因素分析

俞华，刘寰忠，刘强，杨克飞，孙业桓

1.安徽医科大学公共卫生学院，安徽合肥 230032；2.安徽医科大学附院巢湖医院眼科，安徽合肥 243011； 3.安徽医科大学附院巢湖医院精神科，安徽合肥 243011

收稿日期:2019-12-19 修回日期:2020-03-12 接受日期:2020-03-12 出版日期:2020-03-31 发布日期:2020-03-12
通讯作者: 孙业桓
作者简介:俞华，女，1972年生，硕士，研究方向：公共卫生流行病学调查，E-mail：yu_hua66@126.com
基金资助:
安徽省重点研究与开发计划项目（1804h08020263）资助.

Analysis of anxiety and depression status and influencing factors in diabetic patients with or without retinopathy

YU Hua, LIU Huanzhong, LIU Qiang, YANG Kefei, SUN Yehuan

1. Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei 230032, China; 2. Department of Ophthalmology, Chaohu Hospital of Anhui Medical University, Hefei 243011, China; 3. Department of Psychiatry, Chaohu Hospital of Anhui Medical University, Hefei 243011, China

Received:2019-12-19 Revised:2020-03-12 Accepted:2020-03-12 Online:2020-03-31 Published:2020-03-12

摘要/Abstract

摘要： 目的了解有无视网膜病变的糖尿病患者焦虑、抑郁状态及相关的影响因素.方法选取安徽医科大学附属巢湖医院收治的糖尿病患者225例，其中伴有视网膜病变97例（视网膜病变组，DR组），不伴有视网膜病变128例（无视网膜病变组，NDR组）.采用问卷调查的方式收集患者一般资料，采用汉密尔顿焦虑量表（HAMA）和汉密尔顿抑郁量表（HAMD）评估患者的焦虑和抑郁状况.比较两组患者焦虑和抑郁发生率及得分，评估两组患者焦虑和抑郁状态的影响因素.结果 DR组的焦虑和抑郁发生率均高于NDR组，差异具有统计学意义（焦虑：χ2=13.049，P<0.001；抑郁：χ2=13.049，P<0.001）；且DR组的焦虑和抑郁得分均高于NDR组，差异具有统计学意义（焦虑：t=-6.628，P<0.001；抑郁：t=-4.599，P<0.001）.经单因素分析，性别、年龄、患糖尿病的时间、月收入、对自己的病情的了解程度、了解糖尿病会引起视网膜病变、眼视力、是否进行眼科检查等因素是糖尿病患者焦虑评分的影响因素（t/F=-3.795、4.364、-7.079、5.213、3.117、-4.702、20.793、-5.087，P<0.05）；性别、患糖尿病的时间、月收入、了解糖尿病会引起视网膜病变、眼视力、是否进行眼科检查等因素是糖尿病患者抑郁评分的影响因素（t/F=-2.363、-5.162、3.844、-2.707、12.638、-2.586，P<0.05）.多元线性回归分析结果表明，性别、年龄、对自己的病情的了解程度、眼视力是糖尿病患者焦虑评分的影响因素，性别和眼视力是糖尿病患者抑郁评分的影响因素.结论糖尿病视网膜病变患者较无视网膜病变患者的焦虑、抑郁水平升高.性别、年龄、患糖尿病的时间、月收入、对自己的病情的了解程度、眼视力等是糖尿病患者焦虑和抑郁评分的影响因素.有必要给予针对性的干预，以改善患者生活质量.

关键词: 糖尿病, 视网膜病变, 焦虑, 抑郁, 影响因素

Abstract: The aim of the present study was to explore the anxiety and depression status and influencing factors of diabetic patients with or without retinopathy. A total of 225 diabetic patients of Chaohu Hospital of Anhui Medical University were enrolled in the study, including 97 patients with retinopathy (diabetic retinopathy group, DR group) and 128 patients without retinopathy (non-diabetic retinopathy group, NDR group). The patient's general data were collected by questionnaire, and the Hamilton Anxiety Scale (HAMA) and Hamilton Depression Scale (HAMD) were used to assess the incidence and scores of anxiety and depression. The incidence and scores of anxiety and depression were compared between the two groups. The influencing factors of anxiety and depression status were evaluated. The results show that the incidence of anxiety and depression in DR group was higher than that in NDR group (anxiety: χ2=13.049, P<0.001; depression: χ2=13.049, P<0.001); and the scores of anxiety and depression in DR group were higher than those in NDR group (anxiety: t=-6.628, P<0.001; depression: t=-4.599, P<0.001). A univariate analysis reveals that gender, age, diabetes duration, monthly income, understanding of their own condition, understanding that diabetes can cause retinopathy, visual acuity, and ophthalmology were the influencing factors of anxiety scores in diabetic patients (t/F=-3.795, 4.364, -7.079, 5.213, 3.117, 4.702, 20.793, 5.087, P<0.05). Gender, diabets duration, monthly income, understanding that diabetes can cause retinopathy, visual acuity, and ophthalmology were the influencing factors of depression scores in diabetic patients (t/F=-2.363, -5.162, 3.844, -2.707, 12.638, -2.586, P<0.05). The results of multiple linear regression showed that gender, age, understanding of their condition, and visual acuity were the influencing factors of anxiety scores in diabetic patients. Gender and visual acuity were the influencing factors of depression score in diabetic patients. Patients with diabetic retinopathy have higher levels of anxiety and depression than those without retinopathy. Gender, age, time of diabetes, monthly income, understanding of their own condition, and visual acuity were the influencing factors of anxiety and depression scores in diabetic patients. It is necessary to give corresponding intervention to these factors so as to improve the quality of life of diabetic patients.

Key words: Diabetes mellitus, Retinopathy, Anxiety, Depression, Influencing factors

中图分类号:

R774.1

俞华，刘寰忠，刘强，杨克飞，孙业桓. 有无视网膜病变的糖尿病患者焦虑、抑郁状态及影响因素分析[J]. 中国科学技术大学学报, 2020, 50(3): 382-388.

YU Hua, LIU Huanzhong, LIU Qiang, YANG Kefei, SUN Yehuan. Analysis of anxiety and depression status and influencing factors in diabetic patients with or without retinopathy[J]. Journal of University of Science and Technology of China, 2020, 50(3): 382-388.

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有无视网膜病变的糖尿病患者焦虑、抑郁状态及影响因素分析

Analysis of anxiety and depression status and influencing factors in diabetic patients with or without retinopathy

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