Abstract: The ambient VOCs were monitored in the urban area of Hefei city during four seasons in 2016. They were analyzed using an off-line analysis method of SUMMA cannister sampling and gas chromatography-mass spectrometer（GC-MS）. The VOCs results show that 48 VOCs are identified in the air samples including alkane, arene, halohydrocarbon, etc. The annual mean concentration of total VOCs (TVOCs) is 15.61×10-9, the largest one reaching 47.64×10-9. The seasonal variation of TVOCs in this area is obvious, and the order is winter>spring>autumn>summer; the daily mean concentration of TVOCs shows a trend of concentrations being higher in the morning and in the evening, and lower at noontime. Non-carcinogenic risk indexes of VOCs are below 1, which would not cause non-carcinogenic health hazards to exposed populations. However，the cancer risk index exposed to carcinogenic VOCs is higher than the suggested value of USEPA(U. S. Environmental Protection Agency)( 1×10-6 ), which could indicate a relatively higher cancer risk.