Studies on autophagy induced by nano-C70, nano-C60Cl6 and nano-C60Ph6

doi:10.3969/j.issn.0253-2778.2010.04.002

Journal of University of Science and Technology of China ›› 2010, Vol. 40 ›› Issue (4): 339-345.DOI: 10.3969/j.issn.0253-2778.2010.04.002

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Studies on autophagy induced by nano-C70, nano-C60Cl6 and nano-C60Ph6

SUN Kejing

School of Life Sciences, and Hefei National Laboratory for Physical Sciences at Microscale, University of Science and Technology of China, Hefei 230027, China

Received:2009-05-13 Revised:2009-06-10 Online:2010-04-30 Published:2010-04-30

Abstract

Abstract: In order to further study the autophagy induced by fullerene family and its derivatives, nano-C70, C60Cl6 and C60Ph6 were selectively investigated by means of fluorescence microscope, transmission electron microscope and western blot. The results show that, nano-C70, C60Cl6 and C60Ph6 can form crystal structures in water and induce HeLa cells into autophagy process, which indicates that fullerene family and its derivatives might play a new role in the biomedical field.

Key words: fullerene, nanoparticle, C70, C60Cl6, C60Ph6, autophagy

SUN Kejing, ZHENG Fang, WEN Longping. Studies on autophagy induced by nano-C70, nano-C60Cl6 and nano-C60Ph6[J]. Journal of University of Science and Technology of China, 2010, 40(4): 339-345.

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Studies on autophagy induced by nano-C70, nano-C60Cl6 and nano-C60Ph6

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